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Structured Review

Promega pcat-basic reporter vector
Pcat Basic Reporter Vector, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pcat+basic+reporter+vector/pact+vector/pm32387119-42-31-34
Average 90 stars, based on 1 article reviews
pcat-basic reporter vector - by Bioz Stars, 2026-10
90/100 stars

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Related Articles

Sequencing:

Article Title: 6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner.
Article Snippet: Thiopurine drugs, such as 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) and azathioprine have been applied as immunosuppressive drugs for more than 50 years [1].. 6-MP and 6-TG are mainly used in treating acute lymphoblastic leukemia (ALL) in children and adolescents, while azathioprine is used in the treatment of inflammatory bowel diseases, autoimmune diseases and following organ or tissue transplantation [1].. Thiopurine drugs are inactive in their original form and they require metabolic activation to produce a cytotoxic effect [2].

Amplification:

Article Title: 6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner.
Article Snippet: Thiopurine drugs, such as 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) and azathioprine have been applied as immunosuppressive drugs for more than 50 years [1].. 6-MP and 6-TG are mainly used in treating acute lymphoblastic leukemia (ALL) in children and adolescents, while azathioprine is used in the treatment of inflammatory bowel diseases, autoimmune diseases and following organ or tissue transplantation [1].. Thiopurine drugs are inactive in their original form and they require metabolic activation to produce a cytotoxic effect [2].

Cell Culture:

Article Title: 6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner.
Article Snippet: Thiopurine drugs, such as 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) and azathioprine have been applied as immunosuppressive drugs for more than 50 years [1].. 6-MP and 6-TG are mainly used in treating acute lymphoblastic leukemia (ALL) in children and adolescents, while azathioprine is used in the treatment of inflammatory bowel diseases, autoimmune diseases and following organ or tissue transplantation [1].. Thiopurine drugs are inactive in their original form and they require metabolic activation to produce a cytotoxic effect [2].

Transfection:

Article Title: 6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner.
Article Snippet: Thiopurine drugs, such as 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) and azathioprine have been applied as immunosuppressive drugs for more than 50 years [1].. 6-MP and 6-TG are mainly used in treating acute lymphoblastic leukemia (ALL) in children and adolescents, while azathioprine is used in the treatment of inflammatory bowel diseases, autoimmune diseases and following organ or tissue transplantation [1].. Thiopurine drugs are inactive in their original form and they require metabolic activation to produce a cytotoxic effect [2].

Functional Assay:

Article Title: 6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner.
Article Snippet: Thiopurine drugs, such as 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) and azathioprine have been applied as immunosuppressive drugs for more than 50 years [1].. 6-MP and 6-TG are mainly used in treating acute lymphoblastic leukemia (ALL) in children and adolescents, while azathioprine is used in the treatment of inflammatory bowel diseases, autoimmune diseases and following organ or tissue transplantation [1].. Thiopurine drugs are inactive in their original form and they require metabolic activation to produce a cytotoxic effect [2].

Plasmid Preparation:

Article Title: 6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner.
Article Snippet: Thiopurine drugs, such as 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) and azathioprine have been applied as immunosuppressive drugs for more than 50 years [1].. 6-MP and 6-TG are mainly used in treating acute lymphoblastic leukemia (ALL) in children and adolescents, while azathioprine is used in the treatment of inflammatory bowel diseases, autoimmune diseases and following organ or tissue transplantation [1].. Thiopurine drugs are inactive in their original form and they require metabolic activation to produce a cytotoxic effect [2].



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